CTAGE3P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, CTAGE3P RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CTAGE3P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CTAGE3P RNA is repressed in tumor relative to normal tissue. In most cancer types CTAGE3P is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, KIRC, and COAD are the cancer types where CTAGE3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CTAGE3P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAFemaleII,III,IV−0.144<.00111view →
KIRCAllAll+0.082<.0018view →
COADAllAll+0.097.0056view →
UCECAllIV+0.469.0244view →
BRCAAllAll+0.115<.0014view →
LUADFemaleAll−0.105<.0012view →
PAADFemaleAll+0.100.0192view →
HNSCMaleAll−0.027.0392view →
READAllAll+0.206.0401view →
KICHAllII,III,IV+0.118.0201view →
LIHCAllAll+0.046.0131view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CTAGE3P–THCA

Tumor-vs-normal expression box plot for CTAGE3P RNA in THCA.

Open the THCA breakdown →

Exploration