Across TCGA pan-cancer cohorts, CTAGE16P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CTAGE16P’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where CTAGE16P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CTAGE16P is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.
UCEC, KICH, and KIRC are the cancer types where CTAGE16P tumor–normal differential expression is most reproducible.