CTAGE15

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CTAGE15 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CTAGE15 data layer compared with 17 for mass-spec protein.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher CTAGE15 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CTAGE15 expression acts as an unfavorable survival marker.

GBM are the cancer types where CTAGE15 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMOSMedianAll0.1210.415.0423view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

CTAGE15–GBM (OS)

Kaplan–Meier survival curve for CTAGE15 mutant vs wild-type samples in GBM.

Open the GBM breakdown →

Exploration