Q-omics provides the consensus-scored CTAGE12P profile across patient tissues and cancer cell-line models. CTAGE12P expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in BRCA. Among the 18 cancer types available for tumor–normal comparison, CTAGE12P is differentially expressed in 4, with the highest sampling consensus in KICH. Additionally, CTAGE12P RNA expression shows 6,830 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight BRCA, KICH, and THYM as cancer lineages where CTAGE12P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CTAGE12P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CTAGE12P survival associations across molecular data types. CTAGE12P RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CTAGE12P RNA expression–survival associations across cancer types. High CTAGE12P expression shows unfavorable associations in BRCA, BLCA, CHOL, STAD and CESC, but favorable associations in READ. The BRCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .004). Together, the overview and detailed table identify BRCA as the clearest survival context for CTAGE12P RNA expression.
This table summarizes CTAGE12P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for CTAGE12P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CTAGE12P shows lower tumor expression in KICH and higher tumor expression in LUSC, LUAD and KIRC. The KICH box plot shows higher CTAGE12P RNA expression in normal versus tumor tissue (log2 FC = −0.035, t-test p = .002).
This table shows molecular features associated with CTAGE12P in patient tissues and cancer cell lines. In patient samples, CTAGE12P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
