Across TCGA patient cohorts, CTAGE1 mutation is significantly associated with the RNA expression of many other genes, with 4,340 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTAGE1-associated genes across cancer lineages are PIMREG, SPC25, and CDC25C. Each is linked with CTAGE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CTAGE1-to-partner and partner-to-CTAGE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTAGE1→partner) and Y-score (partner→CTAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIMREG →	+0.837	+1.828	<.001	<.001	3	5
UCEC	SPC25 →	+0.549	+1.617	.001	.001	3	4
UCEC	CDC25C →	+0.408	+1.627	.009	.001	3	4
UCEC	POC1A →	+0.528	+1.807	<.001	<.001	3	4
UCEC	PBK →	+0.928	+2.061	<.001	<.001	3	4
UCEC	ZWILCH →	+0.603	+2.488	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,340 associations by consensus.

Exploration

CTAGE1 survival (RNA) · tumor vs normal (RNA) · all CTAGE1 data types