Across TCGA patient cohorts, CTAGE1 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTAGE1-associated genes across cancer lineages are Caspase-7-cleavedD198, INPP4B, and MEK1. Each is linked with CTAGE1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CTAGE1-to-partner and partner-to-CTAGE1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTAGE1→partner) and Y-score (partner→CTAGE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.524	+1.874	.008	.002	3	4
UCEC	INPP4B →	-0.264	-2.807	.014	.002	3	2
UCEC	MEK1 →	+0.507	+2.201	<.001	<.001	2	3
UCEC	PCNA →	+0.220	+2.201	.002	<.001	3	2
UCEC	Annexin-1 →	+0.662	+2.434	<.001	.001	3	2
UCEC	Shc_pY317 →	-0.181	-1.874	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration

CTAGE1 survival (RNA) · tumor vs normal (RNA) · all CTAGE1 data types