CTAG2

Across TCGA patient cohorts, CTAG2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTAG2-associated genes across cancer lineages are Rad50, STAT3_pY705, and C-Raf. Each is linked with CTAG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTAG2-to-partner and partner-to-CTAG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rad50 grouped by CTAG2-low versus CTAG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTAG2→partner) and Y-score (partner→CTAG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.249	-2.321	.041	.035	3	1
UCEC	STAT3_pY705 →	-0.368	-2.999	.005	.035	3	1
UCEC	C-Raf →	+0.174	+2.321	.015	.035	3	1
UCEC	Cyclin-B1 →	+0.600	+2.321	.033	.035	3	1
UCEC	Bid →	-0.137	-2.321	.022	.035	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Rad50 by CTAG2 expression — UCEC

Explore this box plot interactively →