CT66

Across TCGA pan-cancer cohorts, CT66 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CT66 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CT66 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CT66 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

UCEC, PAAD, and KIRC are the cancer types where CT66 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.784	0.889	<.001	88	view →
PAAD	OS	Tertile	All	0.596	0.263	<.001	73	view →
KIRC	DFS	Tertile	All	0.482	0.708	<.001	67	view →
UCS	DFS	Quartile	II,III,IV	0.702	0.205	<.001	44	view →
LAML	DFS	Quartile	All	0.798	0.377	.005	36	view →
STAD	DFS	Median	All	0.468	0.593	.019	25	view →
LUSC	OS	Tertile	All	0.853	0.734	.007	25	view →
BLCA	OS	Quartile	All	0.644	0.738	.022	22	view →
UVM	DFS	Median	All	0.369	0.721	.008	21	view →
READ	OS	Tertile	All	0.523	0.840	.017	18	view →
LIHC	OS	Quartile	All	0.650	0.850	.007	16	view →
SKCM	OS	Median	II,III,IV	0.679	0.786	.007	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CT66–UCEC (DFS)

Open the UCEC breakdown →