CT55

Across TCGA pan-cancer cohorts, CT55 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CT55 data layer compared with 2 for mutation status.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CT55 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CT55 expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.

SKCM, PAAD, and COAD are the cancer types where CT55 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	All	0.682	0.562	<.001	66	view →
PAAD	DFS	Median	All	0.582	0.424	.006	60	view →
COAD	OS	Tertile	IV	0.350	0.757	.002	37	view →
UCEC	DFS	Median	All	0.535	0.712	.004	28	view →
PRAD	OS	Tertile	All	0.965	1.000	.001	24	view →
BLCA	DFS	Tertile	IV	0.235	0.568	.001	15	view →
STAD	DFS	Median	IV	0.210	0.570	.018	12	view →
DLBC	OS	Tertile	II,III,IV	0.640	1.000	.019	9	view →
MESO	OS	Tertile	All	0.556	0.208	.040	6	view →
UVM	OS	Tertile	All	0.659	0.926	.037	6	view →
BRCA	OS	Quartile	III,IV	0.275	0.607	.010	6	view →
LUAD	DFS	Quartile	IV	0.304	0.837	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CT55–SKCM (DFS)

Open the SKCM breakdown →