CT45A8

Across TCGA patient cohorts, CT45A8 RNA expression is significantly associated with the mutation status of many other genes, with 20 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CT45A8-associated genes across cancer lineages are ITIH6, CHPT1, and PEX6. Each is linked with CT45A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT45A8-to-partner and partner-to-CT45A8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITIH6 grouped by CT45A8-low versus CT45A8-high in KIRC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT45A8→partner) and Y-score (partner→CT45A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	ITIH6 →	+8.025	+0.044	.007	<.001	3	1
KIRC	CHPT1 →	+8.025	+0.044	.007	<.001	3	1
KIRC	PEX6 →	+8.025	+0.044	.007	<.001	3	1
KIRC	NXF5 →	+8.025	+0.044	.007	<.001	3	1
KIRC	ECSIT →	+8.025	+0.044	.007	<.001	3	1
KIRC	NPAS1 →	+8.025	+0.044	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ITIH6 by CT45A8 expression — KIRC

Explore this box plot interactively →