CT45A6

Across TCGA cell cohorts, CT45A6 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible CT45A6-associated genes across cancer lineages are RPE65, AMHR2, and TREML1. Each is linked with CT45A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT45A6-to-partner and partner-to-CT45A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPE65 grouped by CT45A6-low versus CT45A6-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT45A6→partner) and Y-score (partner→CT45A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	RPE65 →	+0.007	+2.754	.003	.008	3	1
BLOOD_Myeloma	AMHR2 →	+0.075	+3.584	.003	.002	3	1
BLOOD_Myeloma	TREML1 →	+0.308	+3.807	.001	<.001	3	1
BLOOD_Myeloma	GPR182 →	+0.129	+3.169	<.001	.008	3	1
BLOOD_Myeloma	FAM9B →	+1.963	+3.070	.002	.008	3	1
BLOOD_Myeloma	MYOZ1 →	+0.026	+3.070	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

RPE65 by CT45A6 expression — BLOOD_Myeloma

Explore this box plot interactively →