CT45A3

Across TCGA pan-cancer cohorts, CT45A3 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated CT45A3 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CT45A3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CT45A3 expression acts as an unfavorable survival marker, although some lineages such as OV and LUAD show a favorable association.

COAD, KIRC, and STAD are the cancer types where CT45A3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	IV	0.101	0.658	<.001	117	view →
KIRC	OS	Tertile	All	0.231	0.665	<.001	108	view →
STAD	DFS	Tertile	II,III,IV	0.389	0.559	.005	66	view →
OV	DFS	Quartile	All	0.232	0.132	.002	64	view →
SCLC	DFS	Tertile	All	0.309	0.663	<.001	57	view →
UCEC	DFS	Tertile	All	0.708	0.855	<.001	54	view →
LAML	DFS	Tertile	All	0.380	0.618	.002	36	view →
LIHC	OS	Tertile	All	0.423	0.699	.001	30	view →
LUSC	DFS	Tertile	III,IV	0.225	0.759	.003	18	view →
SARC	OS	Tertile	All	0.488	0.848	.002	18	view →
ACC	DFS	Tertile	All	0.168	0.599	.022	18	view →
HNSC	OS	Tertile	All	0.573	0.676	.023	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

CT45A3–COAD (OS)

Open the COAD breakdown →