CT45A2

Across TCGA patient cohorts, CT45A2 RNA expression is significantly associated with the mutation status of many other genes, with 5 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible CT45A2-associated genes across cancer lineages are CHRNA2, NRG1, and GLB1L3. Each is linked with CT45A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT45A2-to-partner and partner-to-CT45A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHRNA2 grouped by CT45A2-low versus CT45A2-high in SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT45A2→partner) and Y-score (partner→CT45A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	CHRNA2 →	+6.228	+0.484	.001	<.001	3	1
SCLC	NRG1 →	+6.228	+0.484	.001	<.001	3	1
SCLC	GLB1L3 →	+6.228	+0.484	.001	<.001	3	1
SCLC	RAG1 →	+5.228	+0.363	.002	<.001	3	1
SCLC	ADAM18 →	+4.643	+0.290	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CHRNA2 by CT45A2 expression — SCLC

Explore this box plot interactively →