CT45A1

Across TCGA pan-cancer cohorts, CT45A1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CT45A1 data layer compared with 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CT45A1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CT45A1 expression acts as an unfavorable survival marker, although some lineages such as OV and SKCM show a favorable association.

COAD, KICH, and LIHC are the cancer types where CT45A1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	IV	0.115	0.668	<.001	96	view →
KICH	OS	Tertile	All	0.108	0.881	<.001	90	view →
LIHC	OS	Tertile	All	0.470	0.720	<.001	75	view →
ESCA	DFS	Median	All	0.399	0.574	.006	46	view →
ACC	DFS	Tertile	All	0.210	0.610	.007	39	view →
KIRC	OS	Tertile	All	0.487	0.681	.012	36	view →
SCLC	DFS	Tertile	All	0.123	0.575	.001	36	view →
LAML	DFS	Quartile	All	0.393	0.629	.001	36	view →
OV	DFS	Quartile	All	0.462	0.358	.010	34	view →
THYM	DFS	Tertile	All	0.174	0.813	.029	9	view →
SKCM	OS	Quartile	All	0.881	0.742	.014	8	view →
UCEC	DFS	Tertile	All	0.487	0.725	.021	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

CT45A1–COAD (OS)

Open the COAD breakdown →