CSTL1

Across TCGA patient cohorts, CSTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,933 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CSTL1-associated GO terms across cancer lineages are Mismatch repair, Mitochondrial respiratory chain complex assembly, and Positive regulation of double-strand break repair. Each is linked with CSTL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both CSTL1-to-partner and partner-to-CSTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mismatch repair grouped by CSTL1-low versus CSTL1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTL1→partner) and Y-score (partner→CSTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mismatch repair →	+0.060	+0.408	<.001	<.001	3	19
STAD	Mitochondrial respiratory chain complex assembly →	+0.063	+0.358	<.001	<.001	3	18
STAD	Positive regulation of double-strand break repair →	+0.058	+0.337	<.001	<.001	3	18
STAD	Peptidyl-lysine modification →	+0.056	+0.381	<.001	<.001	3	17
STAD	Mitochondrial gene expression →	+0.068	+0.418	<.001	<.001	3	17
STAD	Positive regulation of DNA repair →	+0.059	+0.403	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,933 associations by consensus.

Mismatch repair by CSTL1 expression — STAD

Explore this box plot interactively →