CSTL1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CSTL1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,169 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSTL1-associated genes across cancer lineages are MRPL37, OTULINL, and CX3CR1. Each is linked with CSTL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSTL1-to-partner and partner-to-CSTL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSTL1 versus MRPL37 in UCEC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTL1→partner) and Y-score (partner→CSTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMRPL37 →+0.736+0.406<.001<.00133
GBMOTULINL →-0.778-0.345.003.00133
GBMCX3CR1 →-1.262-0.284<.001.00233
GBMGGTA1 →-1.079-0.252<.001<.00133
GBMADAM28 →-0.926-0.279<.001.00233
LUADNUDT9P1 →-0.533-0.752.003<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,169 associations by consensus.

CSTL1 vs MRPL37 — UCEC

Per-sample scatter of CSTL1 vs MRPL37 in UCEC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration