CSTL1

Across TCGA cell cohorts, CSTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 711 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible CSTL1-associated GO terms across cancer lineages are Protein targeting, Regulation of type I interferon-mediated signaling pathway, and Regulation of IRE1-mediated unfolded protein response. Each is linked with CSTL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CSTL1-to-partner and partner-to-CSTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting grouped by CSTL1-low versus CSTL1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTL1→partner) and Y-score (partner→CSTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein targeting →	+0.061	+0.270	.001	.008	3	7
STOMACH	Regulation of type I interferon-mediated signaling pathway →	+0.082	+0.335	.001	.005	3	6
PANCREAS	Regulation of IRE1-mediated unfolded protein response →	+0.088	+0.099	.002	.009	3	5
STOMACH	Small GTPase-mediated signal transduction →	+0.073	+0.395	<.001	<.001	3	5
STOMACH	Rho protein signal transduction →	+0.105	+0.290	<.001	.006	3	5
LARGE_INTESTINE	Regulation of lung ciliated cell differentiation →	+0.670	+0.316	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 711 associations by consensus.

Protein targeting by CSTL1 expression — STOMACH

Explore this box plot interactively →