CSTF3

Across TCGA cell cohorts, CSTF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,954 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSTF3-associated GO terms across cancer lineages are DNA-templated DNA replication, DNA integrity checkpoint signaling, and Centrosome cycle. Each is linked with CSTF3 in more than 13 cancer types. Because this analysis shows association rather than direction, both CSTF3-to-partner and partner-to-CSTF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by CSTF3-low versus CSTF3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF3→partner) and Y-score (partner→CSTF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DNA-templated DNA replication →	+0.081	+0.608	<.001	<.001	3	14
BLOOD_Leukemia	DNA integrity checkpoint signaling →	+0.053	+0.450	<.001	<.001	3	13
URINARY_TRACT	Centrosome cycle →	+0.060	+0.733	.005	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Centriole replication →	+0.107	+1.309	.002	<.001	3	12
LIVER	Microtubule polymerization or depolymerization →	+0.128	+0.829	.003	<.001	2	13
STOMACH	Constitutive heterochromatin formation →	+0.084	+0.584	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,954 associations by consensus.

DNA-templated DNA replication by CSTF3 expression — BLOOD_Lymphoma

Explore this box plot interactively →