CSTF2

Across TCGA patient cohorts, CSTF2 protein abundance is significantly associated with the protein abundance of many other proteins, with 28,311 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CSTF2-associated proteins across cancer lineages are CCAR1, SF3A1, and SRSF3. Each is linked with CSTF2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CSTF2-to-partner and partner-to-CSTF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSTF2 versus CCAR1 in GBM, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF2→partner) and Y-score (partner→CSTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CCAR1 →	+0.257	+0.300	<.001	<.001	3	10
GBM	SF3A1 →	+0.309	+0.297	<.001	<.001	3	10
GBM	SRSF3 →	+0.363	+0.298	<.001	<.001	3	10
GBM	WBP11 →	+0.298	+0.267	<.001	<.001	3	10
GBM	IK →	+0.320	+0.321	<.001	<.001	3	10
GBM	MFAP1 →	+0.329	+0.319	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 28,311 associations by consensus.

CSTF2 vs CCAR1 — GBM

Explore this scatter interactively →