CSTF2

Across TCGA cell cohorts, CSTF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,517 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CSTF2-associated GO terms across cancer lineages are Mitotic spindle elongation, Mitotic spindle midzone assembly, and Nuclear histone mRNA catabolic process. Each is linked with CSTF2 in more than 18 cancer types. Because this analysis shows association rather than direction, both CSTF2-to-partner and partner-to-CSTF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle elongation grouped by CSTF2-low versus CSTF2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF2→partner) and Y-score (partner→CSTF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Mitotic spindle elongation →	+0.317	+0.909	<.001	<.001	3	19
OESOPHAGUS	Mitotic spindle midzone assembly →	+0.317	+0.909	<.001	<.001	3	19
URINARY_TRACT	Nuclear histone mRNA catabolic process →	+0.138	+0.827	<.001	.002	3	19
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.118	+1.054	<.001	<.001	3	19
LUNG_NSCLC_LUSC	CENP-A containing chromatin assembly →	+0.163	+1.048	.001	.001	3	18
OESOPHAGUS	Spindle elongation →	+0.271	+0.763	.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,517 associations by consensus.

Mitotic spindle elongation by CSTF2 expression — OESOPHAGUS

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