CSTF1

Across TCGA cell cohorts, CSTF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,750 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSTF1-associated GO terms across cancer lineages are DNA-templated DNA replication, Telomere maintenance in response to DNA damage, and Regulation of double-strand break repair via homologous recombination. Each is linked with CSTF1 in more than 16 cancer types. Because this analysis shows association rather than direction, both CSTF1-to-partner and partner-to-CSTF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by CSTF1-low versus CSTF1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTF1→partner) and Y-score (partner→CSTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication →	+0.128	+0.613	<.001	<.001	3	17
BONE	Telomere maintenance in response to DNA damage →	+0.122	+0.495	.001	.003	3	16
BONE	Regulation of double-strand break repair via homologous recombination →	+0.101	+0.524	<.001	<.001	3	15
BONE	Regulation of DNA recombination →	+0.083	+0.571	<.001	<.001	3	15
BLOOD_Myeloma	Replication fork processing →	+0.112	+1.084	<.001	.001	3	15
OESOPHAGUS	DNA-templated DNA replication maintenance of fidelity →	+0.118	+0.763	.003	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,750 associations by consensus.

DNA-templated DNA replication by CSTF1 expression — BONE

Explore this box plot interactively →