CSTA

Across TCGA patient cohorts, CSTA RNA expression is significantly associated with the protein abundance of many other proteins, with 19,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CSTA-associated proteins across cancer lineages are CAPG, HCLS1, and LPXN. Each is linked with CSTA in more than 6 cancer types. Because this analysis shows association rather than direction, both CSTA-to-partner and partner-to-CSTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSTA versus CAPG in GBM, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CSTA→partner) and Y-score (partner→CSTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAPG →	+0.596	+1.063	<.001	<.001	3	7
OV	HCLS1 →	+0.955	+1.739	<.001	<.001	3	7
GBM	LPXN →	+0.675	+0.968	<.001	<.001	3	7
GBM	SH3BP1 →	+0.344	+0.907	<.001	<.001	3	6
GBM	AIF1 →	+0.968	+1.160	<.001	<.001	3	6
GBM	FERMT3 →	+0.784	+1.215	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,736 associations by consensus.

CSTA vs CAPG — GBM

Explore this scatter interactively →