Across TCGA pan-cancer cohorts, CST9L Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CST9L data layer compared with 18 for mass-spec protein and 4 for mass-spec protein.
The strongest signal is observed in esophageal carcinoma (ESCA), where higher CST9L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CST9L expression acts as an unfavorable survival marker.
ESCA, SKCM, and BLCA are the cancer types where CST9L Mutation most reproducibly stratifies survival.