CST9L

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CST9L Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CST9L data layer compared with 18 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher CST9L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CST9L expression acts as an unfavorable survival marker.

ESCA, SKCM, and BLCA are the cancer types where CST9L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSMedianII,III,IV0.2120.686.00830view →
SKCMOSMedianII,III,IV0.5690.846<.0018view →
BLCADFSMedianIV0.0770.476<.0013view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CST9L–ESCA (OS)

Kaplan–Meier survival curve for CST9L mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration