CST9L

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CST9L mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CST9L data layer compared with 18 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CST9L mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CST9L expression acts as an unfavorable survival marker.

CCRCC, PDAC, and LUAD are the cancer types where CST9L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSQuartileIII,IV0.4530.934.00564view →
PDACOSMedianAll0.2670.612.01019view →
LUADDFSQuartileIII,IV0.3531.000.0243view →
HNSCOSMedianIII,IV0.6410.809.0352view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CST9L–CCRCC (DFS)

Kaplan–Meier survival curve for CST9L mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration