CST9

Across TCGA patient cohorts, CST9 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CST9-associated genes across cancer lineages are MORC1-AS1, RNU6-1318P, and RNA5SP136. Each is linked with CST9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CST9-to-partner and partner-to-CST9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORC1-AS1 grouped by CST9-low versus CST9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST9→partner) and Y-score (partner→CST9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MORC1-AS1 →	+0.058	+4.993	<.001	.002	3	2
UCEC	RNU6-1318P →	+0.424	+3.358	<.001	.006	3	2
UCEC	RNA5SP136 →	+0.433	+3.299	<.001	.006	3	2
SKCM	MIR6081 →	+0.419	+4.578	<.001	<.001	3	2
SKCM	MIR4477A →	+1.148	+4.374	<.001	.001	3	1
SKCM	MIR8053 →	+0.244	+4.328	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

MORC1-AS1 by CST9 expression — SKCM

Explore this box plot interactively →