CST8

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CST8 protein abundance is significantly associated with the protein abundance of many other proteins, with 4,527 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CST8-associated proteins across cancer lineages are GDPGP1, CEP85, and EIF3A_S881. Each is linked with CST8 in more than 2 cancer types. Because this analysis shows association rather than direction, both CST8-to-partner and partner-to-CST8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CST8 versus GDPGP1 in HNSC, with a Pearson correlation of 0.78.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CST8→partner) and Y-score (partner→CST8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCGDPGP1 →+0.720+0.703<.001<.00132
GBMCEP85 →+0.541+0.695<.001<.00132
LUADEIF3A_S881 →-0.887-0.432.001<.00132
OVGOLT1B →+0.910+1.242.001<.00123
GBMPPP2R5D_T63 →+0.911+0.821<.001<.00132
GBMEPG5 →+0.359+0.769<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,527 associations by consensus.

CST8 vs GDPGP1 — HNSC

Per-sample scatter of CST8 vs GDPGP1 in HNSC (Pearson r = 0.78).

Explore this scatter interactively →

Exploration