CST7

Across TCGA cell cohorts, CST7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,995 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CST7-associated GO terms across cancer lineages are Negative regulation of cell adhesion, Regulation of smooth muscle cell-matrix adhesion, and Regulation of focal adhesion assembly. Each is linked with CST7 in more than 7 cancer types. Because this analysis shows association rather than direction, both CST7-to-partner and partner-to-CST7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell adhesion grouped by CST7-low versus CST7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CST7→partner) and Y-score (partner→CST7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cell adhesion →	+0.077	+0.752	.001	.001	3	8
BLOOD_Leukemia	Regulation of smooth muscle cell-matrix adhesion →	+0.933	+2.772	<.001	<.001	3	7
STOMACH	Regulation of focal adhesion assembly →	+0.083	+1.111	.005	.007	3	7
STOMACH	Regulation of cell-substrate junction assembly →	+0.083	+1.111	.005	.007	3	7
BLOOD_Leukemia	Regulation of plasminogen activation →	+0.135	+2.258	<.001	.003	3	7
SKIN	Regulation of protein maturation →	+0.066	+1.113	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,995 associations by consensus.

Negative regulation of cell adhesion by CST7 expression — BONE

Explore this box plot interactively →