CST6

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CST6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,951 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CST6-associated proteins across cancer lineages are PXN, CAST, and KRT80. Each is linked with CST6 in more than 5 cancer types. Because this analysis shows association rather than direction, both CST6-to-partner and partner-to-CST6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CST6 versus PXN in HNSC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CST6→partner) and Y-score (partner→CST6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPXN →+0.298+1.480<.001.00236
UCECCAST →+0.390+1.872<.001<.00136
HNSCKRT80 →+0.952+1.453<.001.00236
GBMLUZP1 →+0.364+0.683<.001<.00136
BRCASPATS2L →+0.494+1.733<.001<.00136
LUADPLAU →+0.693+1.327<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,951 associations by consensus.

CST6 vs PXN — HNSC

Per-sample scatter of CST6 vs PXN in HNSC (Pearson r = 0.32).

Explore this scatter interactively →

Exploration