CST4

Across TCGA patient cohorts, CST4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,998 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CST4-associated GO terms across cancer lineages are Detection of chemical stimulus involved in sensory perception of taste, Sensory perception of bitter taste, and Collagen metabolic process. Each is linked with CST4 in more than 16 cancer types. Because this analysis shows association rather than direction, both CST4-to-partner and partner-to-CST4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of chemical stimulus involved in sensory perception of taste grouped by CST4-low versus CST4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CST4→partner) and Y-score (partner→CST4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Detection of chemical stimulus involved in sensory perception of taste →	+0.073	+0.833	<.001	<.001	3	17
STAD	Sensory perception of bitter taste →	+0.074	+0.878	<.001	<.001	3	16
ESCA	Collagen metabolic process →	+0.064	+1.047	<.001	<.001	3	15
ESCA	Collagen biosynthetic process →	+0.045	+0.583	<.001	<.001	3	15
PAAD	Tendon development →	+0.102	+1.230	<.001	<.001	3	15
ESCA	Regulation of collagen metabolic process →	+0.052	+0.856	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,998 associations by consensus.

Detection of chemical stimulus involved in sensory perception of taste by CST4 expression — STAD

Explore this box plot interactively →