CST3

Across TCGA patient cohorts, CST3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,339 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CST3-associated genes across cancer lineages are NCAPH, KPNA2, and BIRC5. Each is linked with CST3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CST3-to-partner and partner-to-CST3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CST3 versus NCAPH in UCEC, with a Pearson correlation of -0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST3→partner) and Y-score (partner→CST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH →	-0.728	-0.505	<.001	<.001	3	6
HNSC	KPNA2 →	-1.058	-0.437	.001	<.001	3	6
UCEC	BIRC5 →	-1.207	-0.532	<.001	<.001	3	6
HNSC	DDIAS →	-0.798	-0.338	<.001	<.001	3	5
LUAD	CENPI →	-0.944	-0.551	<.001	<.001	3	5
UCEC	RAD51AP1 →	-1.186	-0.740	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,339 associations by consensus.

CST3 vs NCAPH — UCEC

Explore this scatter interactively →