CST2

Across TCGA patient cohorts, CST2 protein abundance is significantly associated with the RNA expression of many other genes, with 523 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CST2-associated genes across cancer lineages are YY1, CCNB1IP1, and TCFL5. Each is linked with CST2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CST2-to-partner and partner-to-CST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CST2 versus YY1 in PDAC, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST2→partner) and Y-score (partner→CST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	YY1 →	-0.550	-0.999	.005	.007	3	1
PDAC	CCNB1IP1 →	-0.703	-1.027	<.001	.004	3	1
PDAC	TCFL5 →	-0.706	-0.913	.006	.002	3	1
PDAC	NAA10 →	-0.328	-0.681	.003	.006	3	1
PDAC	H2AZ2 →	-0.338	-0.728	.001	.002	3	1
PDAC	MINDY4 →	-0.406	-1.118	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 523 associations by consensus.

CST2 vs YY1 — PDAC

Explore this scatter interactively →