CST11

Across TCGA patient cohorts, CST11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,578 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CST11-associated GO terms across cancer lineages are Positive regulation of translation, Negative regulation of mRNA metabolic process, and Regulation of actin nucleation. Each is linked with CST11 in more than 12 cancer types. Because this analysis shows association rather than direction, both CST11-to-partner and partner-to-CST11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation grouped by CST11-low versus CST11-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CST11→partner) and Y-score (partner→CST11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of translation →	+0.051	+0.142	<.001	<.001	3	13
STAD	Negative regulation of mRNA metabolic process →	+0.047	+0.127	<.001	<.001	3	12
ESCA	Regulation of actin nucleation →	+0.043	+0.234	<.001	<.001	3	12
STAD	Protein-containing complex disassembly →	+0.046	+0.143	<.001	<.001	3	12
ESCA	Protein stabilization →	+0.051	+0.227	.001	<.001	3	11
STAD	Protein methylation →	+0.044	+0.158	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,578 associations by consensus.

Positive regulation of translation by CST11 expression — STAD

Explore this box plot interactively →