CST11

Across TCGA patient cohorts, CST11 mutation is significantly associated with the RNA expression of many other genes, with 1,234 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CST11-associated genes across cancer lineages are NT5DC1P1, GEMIN8P3, and RN7SKP128. Each is linked with CST11 in more than 1 cancer types. Because this analysis shows association rather than direction, both CST11-to-partner and partner-to-CST11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NT5DC1P1 grouped by CST11-low versus CST11-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST11→partner) and Y-score (partner→CST11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	NT5DC1P1 →	+0.045	+5.878	<.001	.002	3	2
LUAD	GEMIN8P3 →	+0.112	+4.859	<.001	.004	3	2
SKCM	RN7SKP128 →	+0.148	+4.993	<.001	.002	3	2
SKCM	RNU1-8P →	+0.188	+3.817	.003	.004	3	2
SKCM	RNU6-1156P →	+0.380	+3.265	.002	.009	3	2
SKCM	MTND5P27 →	+0.014	+4.624	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,234 associations by consensus.

NT5DC1P1 by CST11 expression — LIHC

Explore this box plot interactively →