CST11

Across TCGA cell cohorts, CST11 RNA expression is significantly associated with the drug of many other genes, with 127 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CST11-associated genes across cancer lineages are SNX-2112, BAY-61-3606, and STF-62247. Each is linked with CST11 in more than 2 cancer types. Because this analysis shows association rather than direction, both CST11-to-partner and partner-to-CST11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX-2112 grouped by CST11-low versus CST11-high in BREAST.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CST11→partner) and Y-score (partner→CST11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SNX-2112 →	-1.005	-0.206	<.001	.027	3	3
LARGE_INTESTINE	BAY-61-3606 →	-0.691	-0.086	.020	.017	3	2
BREAST	STF-62247 →	-0.442	-0.141	<.001	.027	3	2
BREAST	FR-180204 →	-0.345	-0.100	<.001	.021	3	2
BREAST	Pelitinib →	-0.978	-0.115	.005	.027	3	2
BREAST	KIN001-236 →	-0.317	-0.116	.001	.034	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 127 associations by consensus.

SNX-2112 by CST11 expression — BREAST

Explore this box plot interactively →