CST1

Across TCGA cell cohorts, CST1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,130 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible CST1-associated GO terms across cancer lineages are Regulation of receptor clustering, Positive regulation of binding, and Lysosome organization. Each is linked with CST1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CST1-to-partner and partner-to-CST1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of receptor clustering grouped by CST1-low versus CST1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CST1→partner) and Y-score (partner→CST1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of receptor clustering →	+0.122	+1.391	.003	.002	3	5
PANCREAS	Positive regulation of binding →	+0.084	+2.196	<.001	<.001	3	5
SKIN	Lysosome organization →	+0.051	+1.765	<.001	<.001	3	4
SKIN	Lytic vacuole organization →	+0.051	+1.765	<.001	<.001	3	4
STOMACH	Rho protein signal transduction →	+0.090	+1.410	.001	<.001	3	4
PANCREAS	Positive regulation of matrix metallopeptidase secretion →	-0.266	-2.756	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,130 associations by consensus.

Regulation of receptor clustering by CST1 expression — STOMACH

Explore this box plot interactively →