CSRP3

Across TCGA cell cohorts, CSRP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,088 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CSRP3-associated GO terms across cancer lineages are Positive regulation of protein catabolic process, Positive regulation of neuromuscular junction development, and Tubulin deacetylation. Each is linked with CSRP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CSRP3-to-partner and partner-to-CSRP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein catabolic process grouped by CSRP3-low versus CSRP3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRP3→partner) and Y-score (partner→CSRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein catabolic process →	+0.039	+0.040	.003	.008	3	5
BLOOD_Lymphoma	Positive regulation of neuromuscular junction development →	+0.121	+0.022	.003	.004	3	4
SOFT_TISSUE	Tubulin deacetylation →	+0.111	+1.455	<.001	.003	3	4
SKIN	Regulation of organelle assembly →	+0.023	+0.033	.002	.006	3	4
UPPER_AERODIGESTIVE_TRACT	Negative regulation of non-canonical NF-kappaB signal transduction →	+0.088	+0.030	.004	.003	3	3
UPPER_AERODIGESTIVE_TRACT	Regulation of amyloid-beta formation →	+0.074	+0.030	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,088 associations by consensus.

Positive regulation of protein catabolic process by CSRP3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →