CSRP2

Across TCGA cell cohorts, CSRP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,039 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSRP2-associated GO terms across cancer lineages are Mitotic spindle organization, Chromosome segregation, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with CSRP2 in more than 13 cancer types. Because this analysis shows association rather than direction, both CSRP2-to-partner and partner-to-CSRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle organization grouped by CSRP2-low versus CSRP2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRP2→partner) and Y-score (partner→CSRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic spindle organization →	+0.102	+2.143	<.001	<.001	3	14
OESOPHAGUS	Chromosome segregation →	+0.113	+2.451	<.001	<.001	3	14
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.100	+2.128	<.001	.002	3	14
OESOPHAGUS	Mitotic nuclear division →	+0.121	+2.665	<.001	<.001	3	14
STOMACH	Regulation of chromosome organization →	+0.073	+3.139	.001	<.001	3	14
OESOPHAGUS	Spindle assembly →	+0.085	+2.248	.007	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,039 associations by consensus.

Mitotic spindle organization by CSRP2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →