CSRP1

Across TCGA pan-cancer cohorts, CSRP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CSRP1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher CSRP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CSRP1 expression acts as an unfavorable survival marker.

GBM, CCRCC, and PDAC are the cancer types where CSRP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Median	All	0.227	0.593	.001	34	view →
CCRCC	DFS	Median	III,IV	0.145	0.774	.016	25	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LSCC	DFS	Quartile	II,III,IV	0.529	0.882	.021	6	view →
HNSC	DFS	Median	III,IV	0.916	0.988	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CSRP1–GBM (OS)

Open the GBM breakdown →