CSRNP3

Across TCGA patient cohorts, CSRNP3 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSRNP3-associated genes across cancer lineages are Caspase-7-cleavedD198, FASN, and Shc_pY317. Each is linked with CSRNP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CSRNP3-to-partner and partner-to-CSRNP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by CSRNP3-low versus CSRNP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRNP3→partner) and Y-score (partner→CSRNP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.839	+2.459	<.001	<.001	3	5
STAD	FASN →	+0.466	+2.185	.017	.032	3	3
UCEC	Shc_pY317 →	-0.221	-2.459	<.001	<.001	3	3
UCEC	Notch1 →	+0.212	+3.713	<.001	<.001	3	3
STAD	PCNA →	+0.450	+3.321	<.001	.008	3	2
STAD	4E-BP1 →	+0.466	+3.321	<.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Caspase-7-cleavedD198 by CSRNP3 expression — UCEC

Explore this box plot interactively →