CSRNP3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CSRNP3 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CSRNP3-associated genes across cancer lineages are HRK, GADL1, and DIRAS2. Each is linked with CSRNP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSRNP3-to-partner and partner-to-CSRNP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HRK grouped by CSRNP3-low versus CSRNP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRNP3→partner) and Y-score (partner→CSRNP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaHRK →+1.181+3.321.002.00931
BLOOD_LeukemiaGADL1 →+0.571+3.662<.001.00331
BLOOD_LeukemiaDIRAS2 →+0.079+4.502<.001.00131
BLOOD_LeukemiaPRIMA1 →+0.027+2.926<.001.00931
BLOOD_LeukemiaDIP2C-AS1 →+0.181+3.218<.001.00431
BLOOD_LeukemiaTAFA1 →+0.469+3.149.007.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

HRK by CSRNP3 expression — BLOOD_Leukemia

Box plot of HRK in CSRNP3-low vs CSRNP3-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration