CSRNP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CSRNP1 mutation is significantly associated with the RNA expression of many other genes, with 3,000 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSRNP1-associated genes across cancer lineages are RNA5SP422, MIR6077, and KMT5AP1. Each is linked with CSRNP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSRNP1-to-partner and partner-to-CSRNP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by CSRNP1-low versus CSRNP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRNP1→partner) and Y-score (partner→CSRNP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP422 →+0.744+1.848<.001<.00133
SKCMMIR6077 →+0.276+2.625.001.00432
UCECKMT5AP1 →+0.196+1.280<.001.00932
UCECRNA5SP412 →+0.532+1.782<.001.00132
UCECCCDC3 →-0.636-1.807.003<.00132
UCECKLHL21 →+0.390+2.415.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,000 associations by consensus.

RNA5SP422 by CSRNP1 expression — UCEC

Box plot of RNA5SP422 in CSRNP1-low vs CSRNP1-high samples in UCEC.

Explore this box plot interactively →

Exploration