CSRNP1

Across TCGA patient cohorts, CSRNP1 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSRNP1-associated genes across cancer lineages are eEF2, PKC-delta_pS664, and 4E-BP1. Each is linked with CSRNP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CSRNP1-to-partner and partner-to-CSRNP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by CSRNP1-low versus CSRNP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSRNP1→partner) and Y-score (partner→CSRNP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.405	+1.765	<.001	.013	3	3
SKCM	PKC-delta_pS664 →	-0.249	-3.000	.019	.036	3	2
SKCM	4E-BP1 →	+0.351	+3.000	.044	.036	3	2
UCEC	Cyclin-B1 →	+0.658	+2.502	<.001	.001	3	2
UCEC	FASN →	+0.277	+1.584	.030	.034	3	2
UCEC	Akt_pT308 →	+0.410	+1.700	.045	.040	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

eEF2 by CSRNP1 expression — UCEC

Explore this box plot interactively →