CSPP1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CSPP1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CSPP1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CSPP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CSPP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC and CCRCC are the cancer types where CSPP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianIII,IV0.8800.427.02416view →
CCRCCDFSTertileII,III,IV1.0000.404.0405view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CSPP1–UCEC (DFS)

Kaplan–Meier survival curve for CSPP1 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration