CSPG5

Across TCGA cell cohorts, CSPG5 mutation is significantly associated with the RNA expression of many other genes, with 789 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CSPG5-associated genes across cancer lineages are OR56A5, OR1L3, and KRTAP5-11. Each is linked with CSPG5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSPG5-to-partner and partner-to-CSPG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A5 grouped by CSPG5-low versus CSPG5-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSPG5→partner) and Y-score (partner→CSPG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR56A5 →	+0.075	+3.927	<.001	.004	3	2
LUNG_NSCLC_LUAD	OR1L3 →	+0.032	+4.887	<.001	.009	3	2
LUNG_NSCLC_LUAD	KRTAP5-11 →	+0.069	+4.887	<.001	.009	3	2
SOFT_TISSUE	H2BC1 →	+0.325	+4.977	<.001	.002	3	1
SOFT_TISSUE	H2AC1 →	+0.145	+4.977	<.001	.002	3	1
SOFT_TISSUE	FOXR1 →	+0.084	+4.222	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 789 associations by consensus.

OR56A5 by CSPG5 expression — BLOOD_Lymphoma

Explore this box plot interactively →