CSPG4P11

Across TCGA pan-cancer cohorts, CSPG4P11 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CSPG4P11 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CSPG4P11 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CSPG4P11 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

KIRC, KICH, and HNSC are the cancer types where CSPG4P11 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.316	0.631	<.001	119	view →
KICH	DFS	Median	III,IV	0.247	1.000	.001	56	view →
HNSC	DFS	Quartile	IV	0.750	0.573	.005	28	view →
UCS	OS	Median	II,III,IV	0.676	0.249	.003	22	view →
MESO	OS	Tertile	IV	0.178	0.799	.010	15	view →
CHOL	DFS	Quartile	All	0.181	0.634	<.001	12	view →
BLCA	OS	Median	III,IV	0.458	0.306	.005	12	view →
LIHC	OS	Quartile	II,III,IV	0.946	0.664	.013	12	view →
READ	DFS	Tertile	IV	0.179	0.936	.010	9	view →
CESC	DFS	Median	III,IV	0.217	0.609	.029	8	view →
SKCM	OS	Median	III,IV	0.786	0.624	.015	7	view →
ESCA	DFS	Quartile	All	0.369	0.545	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

CSPG4P11–KIRC (DFS)

Open the KIRC breakdown →