CSPG4BP

Across TCGA pan-cancer cohorts, CSPG4BP RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CSPG4BP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CSPG4BP RNA is repressed in tumor relative to normal tissue. In most cancer types CSPG4BP is over-expressed in tumor, although a few such as KIRP and KIRC show the opposite, repressed pattern.

KIRP, KIRC, and KICH are the cancer types where CSPG4BP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CSPG4BP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.824	<.001	11	view →
KIRC	Male	All	−0.743	<.001	11	view →
KICH	Female	II,III,IV	−1.282	<.001	10	view →
THCA	Male	II,III,IV	−0.183	<.001	9	view →
HNSC	All	IV	+0.026	.025	5	view →
UCEC	All	IV	+0.095	.002	2	view →
CHOL	All	All	+0.086	.018	2	view →
LUSC	Male	All	+0.047	.026	2	view →
LIHC	All	All	+0.027	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CSPG4BP–KIRP

Open the KIRP breakdown →