CSPG4

Across TCGA patient cohorts, CSPG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,480 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CSPG4-associated proteins across cancer lineages are SPARC, CLEC3B, and FERMT2. Each is linked with CSPG4 in more than 6 cancer types. Because this analysis shows association rather than direction, both CSPG4-to-partner and partner-to-CSPG4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CSPG4 versus SPARC in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CSPG4→partner) and Y-score (partner→CSPG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SPARC →	+0.879	+0.918	<.001	<.001	3	7
CCRCC	CLEC3B →	+0.645	+0.692	<.001	.005	3	7
OV	FERMT2 →	+0.609	+1.127	<.001	<.001	3	7
OV	LAMA4 →	+0.693	+0.889	<.001	<.001	3	7
CCRCC	MCAM →	+0.594	+1.232	<.001	<.001	3	7
UCEC	PALLD →	+0.750	+0.632	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,480 associations by consensus.

CSPG4 vs SPARC — OV

Explore this scatter interactively →