CSNK2A1

Across TCGA pan-cancer cohorts, CSNK2A1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CSNK2A1 data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CSNK2A1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CSNK2A1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, GBM, and CCRCC are the cancer types where CSNK2A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.925	0.718	.002	27	view →
GBM	DFS	Median	All	0.470	0.287	.007	20	view →
CCRCC	DFS	Tertile	All	0.665	0.875	.011	14	view →
PDAC	DFS	Tertile	All	0.636	0.880	.013	5	view →
UCEC	OS	Median	All	0.908	0.989	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CSNK2A1–LSCC (OS)

Open the LSCC breakdown →