CSNK2A1

Across TCGA patient cohorts, CSNK2A1 mutation is significantly associated with the RNA expression of many other genes, with 1,987 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CSNK2A1-associated genes across cancer lineages are MTND5P27, NDUFS5P6, and OOSP1P1. Each is linked with CSNK2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK2A1-to-partner and partner-to-CSNK2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND5P27 grouped by CSNK2A1-low versus CSNK2A1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK2A1→partner) and Y-score (partner→CSNK2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND5P27 →	+0.102	+4.917	.002	.003	3	2
COAD	NDUFS5P6 →	+0.189	+4.547	.001	.005	3	2
LUAD	OOSP1P1 →	+0.158	+6.739	<.001	<.001	3	2
LUAD	SSX2 →	+0.320	+5.481	<.001	.005	3	2
LUAD	SCGB1D5P →	+0.165	+6.315	<.001	.001	3	2
SKCM	MIR3667 →	+0.891	+4.410	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,987 associations by consensus.

MTND5P27 by CSNK2A1 expression — COAD

Explore this box plot interactively →