CSNK2A1

Across TCGA cell cohorts, CSNK2A1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CSNK2A1-associated genes across cancer lineages are SCGB2A1, CSN1S1, and C8orf74. Each is linked with CSNK2A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CSNK2A1-to-partner and partner-to-CSNK2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB2A1 grouped by CSNK2A1-low versus CSNK2A1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CSNK2A1→partner) and Y-score (partner→CSNK2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SCGB2A1 →	+0.330	+4.169	<.001	.008	3	1
CNS	CSN1S1 →	+1.464	+4.643	<.001	.003	3	1
CNS	C8orf74 →	+0.061	+4.315	<.001	.006	3	1
CNS	GPHB5 →	+0.127	+5.357	<.001	.001	3	1
CNS	SLC36A3 →	+0.006	+4.643	.002	.003	3	1
CNS	AMY1C →	+0.072	+4.472	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

SCGB2A1 by CSNK2A1 expression — CNS

Explore this box plot interactively →